Newcastle United travel to Old Trafford for a replay of last year's Carabao Cup final where the Magpies lost 2-0 to Manchester United at Wembley.
The fixture lands at a tricky time for both clubs for very different reasons.
Both managers are under a different kind of pressure going into the game
Eddie Howe's Newcastle are in the midst of an injury crisis. There's a desperate need to rotate the squad due to a packed schedule, but Howe finds himself with a barebones squad to choose from.
On the other side, Erik ten Hag is facing pressure after a string of poor performances and questionable decisions and will feel he needs a win to save his job.
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Newcastle lost to the Red Devils in last year's final
What channel is showing Manchester United v Newcastle United?
It's going to be a tense game and in the UK you can watch it live on Sky Sports Football on Wednesday 1st November. Kick-off is at 8:15 pm.